I did that last year with no ill effects. Flush with copious amount of water in spring.
Sanitize fresh water tank and flush a couple of times and you should be good.
But!!!! you're probably going to need to get in there eventually, better at home than on the road.
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Dan & Serena
2019 GMC SIERRA 2500 HD SLE
2015 Cougar X-Lite 29 RET
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