Yes, if you lower The middle jacks the weight will be taken off either the front or back jacks probably the back. I tried with my electric jacks down to just take some weight off them with the screw jacks...then I'd have eight feet down
It was very difficult/impossible to apply the same pressure on all six jacks when doing it manually and not have some loose. The best thing for me is the screw type jacks. What I do onsite is get level and extend down the electric stabilizers then finish hook ups and slide outs. After that's done and the tires have cooled, I install those four other screw jacks and crank them down tight so the electric jacks are loose. I leave them it that position until we leave then unscrew them putting the weight back onto the electric jacks. Close up, unhook... then retract the jacks putting even pressure on the RV frame.